Below is a list of our program faculty along with their research interests and mentoring activities within the last year. Please visit their individual web pages for further information. Core faculty may be primary mentors of BMI PhD students. Affiliate faculty may co-mentor BMI PhD students with a core faculty member.
Core Faculty
Reza Abbasi-Asl
Assistant Professor, Neurology
Research summary: Multi-modal data integration and pattern discovery in brain through interpretable machine learning
Nadav Ahituv
Professor, Bioengineering & Therapeutic Sciences
Research summary: Deciphering the role of gene regulatory sequences in human biology and disease
Steven Altschuler
he/him/hisProfessor, Pharmaceutical Chemistry
Research summary: Systems pharmacology and quantitative cell biology for drug discovery in cancer, intestinal and neurodegenerative diseases
Shea Andrews
Research summary: The Andrews Lab focuses on determining the causal pathways that underlie the development of Alzheimer’s disease and related dementias (ADRD) by applying statistical genetic and genetic epidemiological approaches to large genetic & phenotypic datasets.
Rima Arnaout
Assistant Professor, Cardiology
Research summary: Developing computational methods for precision cardiovascular phenotyping
Sergio Baranzini
Professor, Neurology
Research summary: Knowledge representation, knowledge graphs and explainable AI for multi-modal data integration.
Diego Calderon
Bioengineering & Therapeutic Sciences
Research summary: My lab studies how DNA is translated into life and how genetic mutations can lead to disease using cutting-edge computational and experimental techniques.
Tony Capra
Professor, Bioengineering & Therapeutic Sciences
Research summary: Using the tools of computer science and statistics to address problems in evolution, genetics, and biomedicine
William Chen
Research summary: Leveraging AI and computer vision to next-generation digital pathology to elucidate new prostate cancer biomarkers
Ryan Corces
Assistant Professor, Gladstone Institutes
Research summary: Functional epigenomics to decipher the gene regulatory underpinnings of neurodegeneration
Gabriela Fragiadakis
Assistant Professor, Medicine
Research summary: My lab studies states of the human immune system across disease contexts using single-cell methods and data integration, including CyTOF and single-cell sequencing.
Luke Gilbert
Assistant Professor, Urology
Research summary: Synthetic biology, functional genomics and cancer biology
Hani Goodarzi
he/him/hisCore Investigator, Arc Institute; Associate Professor, Biochemistry & Biophysics
Research summary: Research at the intersection of AI and biology to reveal mechanistic insights into how gene expression is regulated at the post-transcriptional level, and how pathological RNA regulation leads of human diseases
Peng He
Research summary: We develop computational methods and construct high-resolution single-cell and spatial maps of human tissues and organoids across development, disease and experimental perturbations.
Ryan Hernandez
Professor
Research summary: Human population genomics, computational and statistical inference, and analysis of genome resequencing data.
Jill Hollenbach
Associate Professor, Neurology
Research summary: Analysis of the extremely polymorphic human leukocyte antigen (HLA) and killer immunoglobulin-like receptor (KIR) immunogenetics systems
Julian Hong
Research summary: The Hong Lab works end-to-end through development, validation, and evaluation to bring computational tools to the cancer clinic.
Franklin Huang
Assistant Professor, Hematology & Oncology
Research summary: Cancer genomics, cancer disparities, prostate cancer, cellular immortality/mechanisms and genomics of telomere maintenance, cancer computational biology
Martin Kampmann
he/him/hisProfessor, Biochemistry & Biophysics
Research summary: Protein homeostasis in normal & disease states of human cells, in particular neurodegeneration
Tanja Kortemme
she/her/hersProfessor, Bioengineering & Therapeutic Sciences
Research summary: Computational biology, prediction and design of protein interactions and networks, synthetic biology
Hao Li
Professor, Biochemistry & Biophysics
Research summary: Bioinformatics, genome sequence analysis, gene regulation
*DEI/Mentorship Training Verified 2022
Jingjing Li
Assistant Professor, Neurology
Research summary: Large-scale analysis of disease genomes by integrating multi-omics data, evolutionary insights, electronic health records, as well as digitized clinical traits from imaging and wearable sensor readouts
Sharmila Majumdar
Professor, Radiology
Research summary: My research interest in applying computer vision and artificial intelligence across the medical imaging lifecycle, from acquisition, quantitative analysis to disease characterization in large datasets.
Nicola Mueller
Medicine-SFGH
Research summary: The Müller lab at the EPPIcenter aims to quantify transmission dynamics of bacterial and viral infectious diseases from pathogen genome sequence data, with the ultimate goal of informing public health interventions to reduce disease burden
Tomasz Nowakowski
Research summary: Dr. Nowakowski seeks to uncover genetic control mechanisms underlying neurodevelopmental events and tissue organization in the cerebral cortex, and highlight and cellular patterns of selective vulnerability in neurodevelopmental and neuropsychiatric disorders, including Autism Spectrum Disorders and Schizophrenia.
Vasilis Ntranos
Assistant Professor, Epidemiology & Biostatistics, Diabetes Center
Research summary: Computational methods development at the intersection of information theory, genomics and machine learning, with a focus on single cell biology and alternative splicing
Lorenzo Pasquini
Assistant Professor, Neurology
Research summary: Neuroimaging and neurophysiology, cognitive neuroscience, aging and dementia, loneliness and emotions, psychedelics, digital intervention
Katie Pollard
Professor, Epi & Biostats, Gladstone Institutes
Research summary: Comparative genomics, metagenomics, evolution, machine-learning, multivariate statistics
David Quigley
Assistant Professor, Urology
Research summary: My lab studies identifies genomic and epigenomic mechanisms of resistance to targeted cancer therapy using clinical sequencing data from patient tumors. Projects include novel machine learning methods, developing liquid biomarkers, spatial and single cell analysis, and functional studies.
Vijay Ramani
Assistant Professor, Gladstone Institutes
Research summary: Development of cutting-edge molecular technologies to better understand how genomes are structured, regulated, and interpreted in health and disease
Andrej Sali
Professor, Bioengineering & Therapeutic Sciences
Research summary: Computation grounded in the laws of physics and evolution to study the structure and function of proteins
Yin Shen
Associate Professor, Neurology
Research summary: Investigate genome function using functional genomics, iPSC models, and CRISPR screens.
Brian Shoichet
Professor, Pharmaceutical Chemistry
Research summary: Molecular docking, structure-based inhibitor discovery, G Protein Coupled Receptors, colloidal aggregation and phospholipidosis in drug discovery and formulation, drug discovery for analgesia and psychiatric disorders.
Param Singh
Assistant Professor, Department of Anatomy and Bakar Aging Research Institute
Research summary: Decoding gene regulation during vertebrate diapause, aging and disease
Marina Sirota
Professor, Pediatrics; Acting Director, Bakar Computational Health Sciences Institute
Research summary: Develop integrative computational methods and apply these approaches in the context of disease diagnostics and therapeutics
Jeff Spence
he/him/hisAssistant Professor, Epidemiology & Biostatistics
Research summary: We primarily develop methods and theory to understand how evolution shapes the genetic architecture of complex traits at different biological scales, but we are also broadly interested in any biological puzzles that present interesting computational or statistical challenges.
Matthew Spitzer
Assistant Professor, Otolaryngology, Otolaryngology
Research summary: Systems approaches and single-cell data to understand how the immune system mounts responses, with a specific emphasis in cancer immunology
Madhumita Sushil
Assistant Professor, DoC-IT, Neurological Surgery
Research summary: Dr. Sushil’s team is engaged in the development, application, and validation of multimodal foundation models for electronic health record data to solve clinically relevant and impactful problems within medical informatics.
Catherine Tcheandjieu Gueliatcha
Assistant Professor, Gladstone Institutes
Research summary: Genetic architecture of diseases in diverse populations
https://gladstone.org/people/catherine-tcheandjieu-gueliatcha
Christina Theodoris
Research summary: Our lab develops deep learning models leveraging large-scale biological data to gain a fundamental understanding of gene network dynamics. We integrate AI with experimental genomics in a closed-loop system to accelerate discoveries of key network regulators and network-correcting therapies for human disease.
Dara Torgerson
Associate Adjunct Professor, Epidemiology & Biostatistics
Research summary: Integrative genomic studies of complex disease in diverse populations
Peter Washington
Assistant Professor
Research summary: Informatics methods for digital diagnostics and therapeutics using data from smartphones, wearables, and other consumer devices
Andrew Yang
Assistant Professor, Neurology, Gladstone Institutes
Research summary: Understanding neuroimmune contributions to brain aging and neurodegenerative disease using single-cell and spatial genomics approaches.
Jimmie Ye
Assistant Professor, Epidemiology & Biostatistics
Research summary: Interaction between genetics and environment affect human variation at the level of molecular phenotypes
Elad Ziv
Professor, Medicine, Internal Medicine
Research summary: Application of Population Genetics to the Study of Complex Traits in Humans
Affiliate Faculty
Mark Ansel
Professor,Microbiology & Immunology, & Chair, UCSF Bakar ImmunoX Initiative.
Research summary: RNA Regulation of Immunity
Joseph Bondy-Denomy
Assistant Professor, Microbiology & Immunology
Research summary: CRISPR-Cas Biology and Phage-Bacteria Interactions
Steven Brenner
Professor, UC Berkeley; Adjunct Professor
Research summary: Phenotypic and clinical impacts of human genome variation, Regulation by alternative splicing, protein function prediction
Charles Chiu
Professor, Laboratory Medicine, Laboratory Medicine
Research summary: Viral pathogen discovery and characterization, computational algorithms for metagenomics analysis, and the development and validation of next-generation sequencing-based clinical diagnostics for infectious diseases
Jan Christoph
Assistant Professor, Cardiovascular Research Institute
Research summary: Physics of complex biological systems, artificial intelligence, emergent phenomena in cells and (cardiac) tissues, self-organization, biomechanics and electrophysiology.
Bruce Conklin
Professor, Gladstone Institute of Cardiovascular Disease
Research summary: Therapeutic eding and modeling genetic disease in iPSC-derived neurons and cardiomyocytes
Thomas Hoffmann
Associate Professor, Epidemiology & Biostatistics
Research summary: Developing and applying methods to understand the genetics of complex human diseases
Sandy Johnson
Professor, Microbiology & Immunology
Research summary: Transcription circuits, their evolution, and how they function in microbial pathogenesis
Nevan Krogan
he/him/hisProfessor, Cellular & Molecular Pharmacology
Research summary: Functional Insights from Genetic and Physical Interaction Maps
John Liu
Assistant Professor, Neurological Surgery
Research summary: The Liu Lab develops and applies functional genomic approaches to discover novel therapeutic targets and understand treatment resistance pathways in cancer, with particular interest in brain tumors.
Susan Lynch
Associate Professor, Gastroenterology
Research summary: Our group studies the human microbiome and its capacity to predict, prevent and treat chronic inflammatory disease.
Michael McManus
Associate Professor, Microbiology & Immunology
Research summary: Quantitative biology research lab that uses systematic high-throughput and synthetic approaches to conquer fundamental problems in understanding gene function in health and disease.
Elphege Nora
Research summary: Our group studies the molecular mechanisms of chromosomes folding and how they enable the emergence of genomic functions - with a focus on transcriptional regulation during stem cell differentiation.
Michael Oldham
Associate Professor, Neurological Surgery
Research summary: We develop and apply novel experimental and computational strategies for studying the cellular and molecular organization of human brain samples in health and disease, with an emphasis on adult malignant gliomas
Karin Pelka
Gladstone Institute
Research summary: By using a combination of large-scale genomic analyses and tissue imaging approaches, the Pelka Lab studies the cellular interactions that shape immune responses in human tumors, focusing on how these responses are regulated.
Alex Pollen
Neil Risch
Professor and Director, Institute for Human Genetics
Research summary: Genetic epidemiology of complex diseases in ethnic populations
Vivek Rudrapatna
Research summary: We strive to learn causal effects from electronic health records, and design AI tools to improve diagnosis and treatment decisions in clinical practice, particularly in inflammatory bowel disease.
Mark Segal
Professor, Epidemiology & Biostatistics
Research summary: Statistical and computational methods in genomics with a current emphasis on 3D chromatin conformation.
Mark Seielstad
Professor, Institute for Human Genetics
Research summary: Search for genetic variation underlying complex human diseases of immunity and metabolism
Licia Selleri
Research summary: We study the genetic, transcriptional, and epigenetic regulation of tissue and organ morphogenesis during development and evolution, with a special focus on craniofacial traits
Peter Turnbaugh
Professor, Microbiology & Immunology
Research summary: Impact of the human gut microbiome on pharmacology
Lani Wu
she/her/hersProfessor, Pharmaceutical Chemistry
Research summary: Drug discovery, cancer drug resistance, neurodegeneration, high-throughput imaging, machine learning, organoid models of disease.
In Memoriam Faculty
Atul Butte
Professor, Pediatrics, and Institute Director, Baker Computational Health Sciences Institute, Chief Data Scientist, University of California Health
https://chancellor.ucsf.edu/news/remembering-atul-butte-md-phd
