Faculty

Below is a list of our program faculty along with their research interests and mentoring activities within the last year. Please visit their individual web pages for further information. Core faculty may be primary mentors of BMI PhD students. Affiliate faculty may co-mentor BMI PhD students with a core faculty member.

Core Faculty

Reza Abbasi-Asl

Reza Abbasi-Asl

[email protected]

Assistant Professor, Neurology

Research summary: Multi-modal data integration and pattern discovery in brain through interpretable machine learning

https://abbasilab.org/

Nadav Ahituv

Nadav Ahituv

[email protected]

Professor, Bioengineering & Therapeutic Sciences

Research summary: Deciphering the role of gene regulatory sequences in human biology and disease

https://pharm.ucsf.edu/ahituv

Steven Altschuler

Steven Altschuler

he/him/his

[email protected]

Professor, Pharmaceutical Chemistry

Research summary: Systems pharmacology and quantitative cell biology for drug discovery in cancer, intestinal and neurodegenerative diseases

http://www.AltschulerWuLab.org

Shea Andrews

Shea Andrews

[email protected]

Research summary: The Andrews Lab focuses on determining the causal pathways that underlie the development of Alzheimer’s disease and related dementias (ADRD) by applying statistical genetic and genetic epidemiological approaches to large genetic & phenotypic datasets.

https://andrewslab.ucsf.edu/

Rima Arnaout

Rima Arnaout

[email protected]

Assistant Professor, Cardiology

Research summary: Developing computational methods for precision cardiovascular phenotyping

https://arnaoutlab.ucsf.edu

Sergio Baranzini

Sergio Baranzini

[email protected]

Professor, Neurology

Research summary: Knowledge representation, knowledge graphs and explainable AI for multi-modal data integration.

http://baranzinilab.ucsf.edu/

Diego Calderon

Diego Calderon

[email protected]

Bioengineering & Therapeutic Sciences

Research summary: My lab studies how DNA is translated into life and how genetic mutations can lead to disease using cutting-edge computational and experimental techniques.

Tony Capra

Tony Capra

[email protected]

Professor, Bioengineering & Therapeutic Sciences

Research summary: Using the tools of computer science and statistics to address problems in evolution, genetics, and biomedicine

http://www.capralab.org/

William Chen

William Chen

[email protected]

Research summary: Leveraging AI and computer vision to next-generation digital pathology to elucidate new prostate cancer biomarkers

Ryan Corces

Ryan Corces

[email protected]

Assistant Professor, Gladstone Institutes

Research summary: Functional epigenomics to decipher the gene regulatory underpinnings of neurodegeneration

https://www.corceslab.com/

Joseph DeRisi

Joseph DeRisi

[email protected]

Professor, Biochemistry & Biophysics

Research summary: Infectious Disease, Genomics

https://derisilab.ucsf.edu

Gabriela Fragiadakis

Gabriela Fragiadakis

[email protected]

Assistant Professor, Medicine

Research summary: My lab studies states of the human immune system across disease contexts using single-cell methods and data integration, including CyTOF and single-cell sequencing.

https://dscolab.ucsf.edu/

Luke Gilbert

Luke Gilbert

[email protected]

Assistant Professor, Urology

Research summary: Synthetic biology, functional genomics and cancer biology

https://www.gilbertlabucsf.com/

Hani Goodarzi

Hani Goodarzi

he/him/his

[email protected]

Core Investigator, Arc Institute; Associate Professor, Biochemistry & Biophysics

Research summary: Research at the intersection of AI and biology to reveal mechanistic insights into how gene expression is regulated at the post-transcriptional level, and how pathological RNA regulation leads of human diseases

http://goodarzilab.ucsf.edu/

Peng He

Peng He

[email protected]

Research summary: We develop computational methods and construct high-resolution single-cell and spatial maps of human tissues and organoids across development, disease and experimental perturbations.

https://peng-he-lab.github.io/

Ryan Hernandez

Ryan Hernandez

[email protected]

Professor

Research summary: Human population genomics, computational and statistical inference, and analysis of genome resequencing data.

http://bts.ucsf.edu/hernandez_lab/

Jill Hollenbach

Jill Hollenbach

[email protected]

Associate Professor, Neurology

Research summary: Analysis of the extremely polymorphic human leukocyte antigen (HLA) and killer immunoglobulin-like receptor (KIR) immunogenetics systems

https://hollenbachlab.ucsf.edu

Julian Hong

Julian Hong

[email protected]

Research summary: The Hong Lab works end-to-end through development, validation, and evaluation to bring computational tools to the cancer clinic.

https://honglab.ucsf.edu

Franklin Huang

Franklin Huang

[email protected]

Assistant Professor, Hematology & Oncology

Research summary: Cancer genomics, cancer disparities, prostate cancer, cellular immortality/mechanisms and genomics of telomere maintenance, cancer computational biology

https://franklinhuanglab.ucsf.edu/

Martin Kampmann

Martin Kampmann

he/him/his

[email protected]

Professor, Biochemistry & Biophysics

Research summary: Protein homeostasis in normal & disease states of human cells, in particular neurodegeneration

http://kampmannlab.ucsf.edu

Tanja Kortemme

Tanja Kortemme

she/her/hers

[email protected]

Professor, Bioengineering & Therapeutic Sciences

Research summary: Computational biology, prediction and design of protein interactions and networks, synthetic biology

http://kortemmelab.ucsf.edu/

Hao Li

Hao Li

[email protected]

Professor, Biochemistry & Biophysics

Research summary: Bioinformatics, genome sequence analysis, gene regulation

*DEI/Mentorship Training Verified 2022

http://mobydick.ucsf.edu/~haoli/

Jingjing Li

Jingjing Li

[email protected]

Assistant Professor, Neurology

Research summary: Large-scale analysis of disease genomes by integrating multi-omics data, evolutionary insights, electronic health records, as well as digitized clinical traits from imaging and wearable sensor readouts

https://www.complexdisease.org/

Sharmila Majumdar

Sharmila Majumdar

[email protected]

Professor, Radiology

Research summary: My research interest in applying computer vision and artificial intelligence across the medical imaging lifecycle, from acquisition, quantitative analysis to disease characterization in large datasets.

Nicola Mueller

Nicola Mueller

[email protected]

Medicine-SFGH

Research summary: The Müller lab at the EPPIcenter aims to quantify transmission dynamics of bacterial and viral infectious diseases from pathogen genome sequence data, with the ultimate goal of informing public health interventions to reduce disease burden

https://muellerlab.io/

Tomasz Nowakowski

Research summary: Dr. Nowakowski seeks to uncover genetic control mechanisms underlying neurodevelopmental events and tissue organization in the cerebral cortex, and highlight and cellular patterns of selective vulnerability in neurodevelopmental and neuropsychiatric disorders, including Autism Spectrum Disorders and Schizophrenia.

https://nowakowski-lab.squarespace.com/

Vasilis Ntranos

Vasilis Ntranos

[email protected]

Assistant Professor, Epidemiology & Biostatistics, Diabetes Center

Research summary: Computational methods development at the intersection of information theory, genomics and machine learning, with a focus on single cell biology and alternative splicing

Lorenzo Pasquini

Lorenzo Pasquini

[email protected]

Assistant Professor, Neurology

Research summary: Neuroimaging and neurophysiology, cognitive neuroscience, aging and dementia, loneliness and emotions, psychedelics, digital intervention

https://profiles.ucsf.edu/lorenzo.pasquini

Katie Pollard

Katie Pollard

[email protected]

Professor, Epi & Biostats, Gladstone Institutes

Research summary: Comparative genomics, metagenomics, evolution, machine-learning, multivariate statistics

http://docpollard.org

David Quigley

David Quigley

[email protected]

Assistant Professor, Urology

Research summary: My lab studies identifies genomic and epigenomic mechanisms of resistance to targeted cancer therapy using clinical sequencing data from patient tumors. Projects include novel machine learning methods, developing liquid biomarkers, spatial and single cell analysis, and functional studies.

https://quigleylab.ucsf.edu

Vijay Ramani

Vijay Ramani

[email protected]

Assistant Professor, Gladstone Institutes

Research summary: Development of cutting-edge molecular technologies to better understand how genomes are structured, regulated, and interpreted in health and disease

https://kamakshi.ucsf.edu/

Andrej Sali

Andrej Sali

[email protected]

Professor, Bioengineering & Therapeutic Sciences

Research summary: Computation grounded in the laws of physics and evolution to study the structure and function of proteins

http://www.salilab.org/

Yin Shen

Yin Shen

[email protected]

Associate Professor, Neurology

Research summary: Investigate genome function using functional genomics, iPSC models, and CRISPR screens.

http://shenlab.ucsf.edu/

Brian Shoichet

Brian Shoichet

[email protected]

Professor, Pharmaceutical Chemistry

Research summary: Molecular docking, structure-based inhibitor discovery, G Protein Coupled Receptors, colloidal aggregation and phospholipidosis in drug discovery and formulation, drug discovery for analgesia and psychiatric disorders.

https://bkslab.org/

Param Singh

Param Singh

[email protected]

Assistant Professor, Department of Anatomy and Bakar Aging Research Institute

Research summary: Decoding gene regulation during vertebrate diapause, aging and disease

https://www.singhlabucsf.org

Marina Sirota

Marina Sirota

[email protected]

Professor, Pediatrics; Acting Director, Bakar Computational Health Sciences Institute

Research summary: Develop integrative computational methods and apply these approaches in the context of disease diagnostics and therapeutics

http://sirotalab.ucsf.edu/

Jeff Spence

Jeff Spence

he/him/his

[email protected]

Assistant Professor, Epidemiology & Biostatistics

Research summary: We primarily develop methods and theory to understand how evolution shapes the genetic architecture of complex traits at different biological scales, but we are also broadly interested in any biological puzzles that present interesting computational or statistical challenges.

Matthew Spitzer

Matthew Spitzer

[email protected]

Assistant Professor, Otolaryngology, Otolaryngology

Research summary: Systems approaches and single-cell data to understand how the immune system mounts responses, with a specific emphasis in cancer immunology

https://www.spitzerlab.org/

Madhumita Sushil

Madhumita Sushil

[email protected]

Assistant Professor, DoC-IT, Neurological Surgery

Research summary: Dr. Sushil’s team is engaged in the development, application, and validation of multimodal foundation models for electronic health record data to solve clinically relevant and impactful problems within medical informatics.

Catherine Tcheandjieu Gueliatcha

Catherine Tcheandjieu Gueliatcha

[email protected]

Assistant Professor, Gladstone Institutes

Research summary: Genetic architecture of diseases in diverse populations

https://gladstone.org/people/catherine-tcheandjieu-gueliatcha

Christina Theodoris

Christina Theodoris

[email protected]

Research summary: Our lab develops deep learning models leveraging large-scale biological data to gain a fundamental understanding of gene network dynamics. We integrate AI with experimental genomics in a closed-loop system to accelerate discoveries of key network regulators and network-correcting therapies for human disease.

https://www.theodorislab.gladstone.org/

Dara Torgerson

Dara Torgerson

[email protected]

Associate Adjunct Professor, Epidemiology & Biostatistics

Research summary: Integrative genomic studies of complex disease in diverse populations

Peter Washington

Peter Washington

[email protected]

Assistant Professor

Research summary: Informatics methods for digital diagnostics and therapeutics using data from smartphones, wearables, and other consumer devices

https://www.peterwashington.net

Andrew Yang

Andrew Yang

[email protected]

Assistant Professor, Neurology, Gladstone Institutes

Research summary: Understanding neuroimmune contributions to brain aging and neurodegenerative disease using single-cell and spatial genomics approaches.

https://www.yanglab-ucsf.org/

Jimmie Ye

Jimmie Ye

[email protected]

Assistant Professor, Epidemiology & Biostatistics

Research summary: Interaction between genetics and environment affect human variation at the level of molecular phenotypes

Elad Ziv

Elad Ziv

[email protected]

Professor, Medicine, Internal Medicine

Research summary: Application of Population Genetics to the Study of Complex Traits in Humans

https://zivlab.ucsf.edu/

Affiliate Faculty

Mark Ansel

Mark Ansel

[email protected]

Professor,Microbiology & Immunology, & Chair, UCSF Bakar ImmunoX Initiative.

Research summary: RNA Regulation of Immunity

https://ansel.ucsf.edu/

Joseph Bondy-Denomy

Joseph Bondy-Denomy

[email protected]

Assistant Professor, Microbiology & Immunology

Research summary: CRISPR-Cas Biology and Phage-Bacteria Interactions

https://bondydenomylab.com/

Steven Brenner

Steven Brenner

[email protected]

Professor, UC Berkeley; Adjunct Professor

Research summary: Phenotypic and clinical impacts of human genome variation, Regulation by alternative splicing, protein function prediction

http://compbio.berkeley.edu

Charles Chiu

Charles Chiu

[email protected]

Professor, Laboratory Medicine, Laboratory Medicine

Research summary: Viral pathogen discovery and characterization, computational algorithms for metagenomics analysis, and the development and validation of next-generation sequencing-based clinical diagnostics for infectious diseases

http://chiulab.ucsf.edu

Jan Christoph

Jan Christoph

[email protected]

Assistant Professor, Cardiovascular Research Institute

Research summary: Physics of complex biological systems, artificial intelligence, emergent phenomena in cells and (cardiac) tissues, self-organization, biomechanics and electrophysiology.

https://cardiacvision.ucsf.edu/

Bruce Conklin

Bruce Conklin

[email protected]

Professor, Gladstone Institute of Cardiovascular Disease

Research summary: Therapeutic eding and modeling genetic disease in iPSC-derived neurons and cardiomyocytes

https://labs.gladstone.org/conklin

Thomas Hoffmann

Thomas Hoffmann

[email protected]

Associate Professor, Epidemiology & Biostatistics

Research summary: Developing and applying methods to understand the genetics of complex human diseases

Sandy Johnson

Sandy Johnson

[email protected]

Professor, Microbiology & Immunology

Research summary: Transcription circuits, their evolution, and how they function in microbial pathogenesis

http://johnsonlab.ucsf.edu/

Nevan Krogan

Nevan Krogan

he/him/his

[email protected]

Professor, Cellular & Molecular Pharmacology

Research summary: Functional Insights from Genetic and Physical Interaction Maps

http://kroganlab.ucsf.edu

John Liu

John Liu

[email protected]

Assistant Professor, Neurological Surgery

Research summary: The Liu Lab develops and applies functional genomic approaches to discover novel therapeutic targets and understand treatment resistance pathways in cancer, with particular interest in brain tumors.

https://liulab.ucsf.edu

Susan Lynch

Susan Lynch

[email protected]

Associate Professor, Gastroenterology

Research summary: Our group studies the human microbiome and its capacity to predict, prevent and treat chronic inflammatory disease.

https://lynchlab.ucsf.edu/

Michael McManus

Michael McManus

[email protected]

Associate Professor, Microbiology & Immunology

Research summary: Quantitative biology research lab that uses systematic high-throughput and synthetic approaches to conquer fundamental problems in understanding gene function in health and disease.

http://mcmanuslab.ucsf.edu/

Elphege Nora

Elphege Nora

[email protected]

Research summary: Our group studies the molecular mechanisms of chromosomes folding and how they enable the emergence of genomic functions - with a focus on transcriptional regulation during stem cell differentiation.

https://noralab.ucsf.edu/

Michael Oldham

Michael Oldham

[email protected]

Associate Professor, Neurological Surgery

Research summary: We develop and apply novel experimental and computational strategies for studying the cellular and molecular organization of human brain samples in health and disease, with an emphasis on adult malignant gliomas

https://oldhamlab.ucsf.edu

Karin Pelka

Karin Pelka

[email protected]

Gladstone Institute

Research summary: By using a combination of large-scale genomic analyses and tissue imaging approaches, the Pelka Lab studies the cellular interactions that shape immune responses in human tumors, focusing on how these responses are regulated.

https://pelkalab.org

Alex Pollen

[email protected]

Neil Risch

Neil Risch

[email protected]

Professor and Director, Institute for Human Genetics

Research summary: Genetic epidemiology of complex diseases in ethnic populations

http://humgen.medschool.ucsf.edu/

Vivek Rudrapatna

Vivek Rudrapatna

[email protected]

Research summary: We strive to learn causal effects from electronic health records, and design AI tools to improve diagnosis and treatment decisions in clinical practice, particularly in inflammatory bowel disease.

https://profiles.ucsf.edu/vivek.rudrapatna

Mark Segal

Mark Segal

[email protected]

Professor, Epidemiology & Biostatistics

Research summary: Statistical and computational methods in genomics with a current emphasis on 3D chromatin conformation.

Mark Seielstad

Mark Seielstad

[email protected]

Professor, Institute for Human Genetics

Research summary: Search for genetic variation underlying complex human diseases of immunity and metabolism

https://profiles.ucsf.edu/mark.seielstad

Licia Selleri

Licia Selleri

[email protected]

Research summary: We study the genetic, transcriptional, and epigenetic regulation of tissue and organ morphogenesis during development and evolution, with a special focus on craniofacial traits

https://selleri.ucsf.edu/

Peter Turnbaugh

Peter Turnbaugh

[email protected]

Professor, Microbiology & Immunology

Research summary: Impact of the human gut microbiome on pharmacology

http://turnbaughlab.ucsf.edu/

Lani Wu

Lani Wu

she/her/hers

[email protected]

Professor, Pharmaceutical Chemistry

Research summary: Drug discovery, cancer drug resistance, neurodegeneration, high-throughput imaging, machine learning, organoid models of disease.

http://www.altschulerwulab.org

In Memoriam Faculty

Atul Butte

Atul Butte

Professor, Pediatrics, and Institute Director, Baker Computational Health Sciences Institute, Chief Data Scientist, University of California Health

https://chancellor.ucsf.edu/news/remembering-atul-butte-md-phd